منابع مشابه
Gone with the Wind--Innate Immunity and Airway Inflammation.
recruitment to the site of inflammation, where CXC chemokines play an essential role, ROS production is an important arm of innate host defense executed by neutrophils [6] . In this issue, Choudhary et al. [7] show that endogenous nuclear ROS sensors transmit nuclear signals that coordinate outside-in pattern recognition receptor signaling, regulating innate immune receptors and thereby playing...
متن کاملInnate Immunity of Airway Epithelium and COPD
The mammalian immune system consists of two branchesinnate and adaptive immune systems and together they provide protection against infection. Innate immunity is a first line of host defense and is responsible for immediate recognition of pathogens to prevent microbial invasion. In addition innate immune responses also stimulate adaptive immune system (Medzhitov and Janeway, 1997). Cellular com...
متن کاملTrauma, Sepsis, Innate, Adaptive Immunity and Inflammation
Introduction: This review paper covered, trauma, sepsis, innate, adaptive immunity and inflammation along with anxiety, and depression that occurs both in women with asthma, traumatic children and adult patients. Materials and Methods: This is a review article. Areas covered include immune function changes, which can lead to both trauma and pro-inflammatory activation known as systemic inflamma...
متن کاملSignalling networks, inflammation and innate immunity.
We have been analysing the signalling systems that couple to receptors of the TIR (Toll/interleukin-1 receptor) family, which signal through a common cytoplasm region; the TIR domain. These systems are of both practical and fundamental biological significance, being central to the pathogenesis of chronic inflammatory diseases such as atherosclerosis, to host defence throughout the biological wo...
متن کاملMitochondrial Control of Innate Immunity and Inflammation
Mitochondria are key organelles involved in energy production, functioning as the metabolic hubs of cells. Recent findings emphasize the emerging role of the mitochondrion as a key intracellular signaling platform regulating innate immune and inflammatory responses. Several mitochondrial proteins and mitochondrial reactive oxygen species have emerged as central players orchestrating the innate ...
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ژورنال
عنوان ژورنال: Journal of Innate Immunity
سال: 2010
ISSN: 1662-8128,1662-811X
DOI: 10.1159/000264603